φρήν properly = διάφραγμα, the midriff or muscle which parts the heart and lungs (viscera thoracis) from the lower viscera (abdominis), Aesch.; usually in pl., Arist., etc. in Hom., φρήν or φρένες the parts about the heart, the breast, Lat. praecordia, Il.; φρένες ἀμφιμέλαιναι Il. the heart, as the seat of the passions, Hom., etc.; ἐκ φρενός from oneʼs very heart, Aesch.; φῦσαι φρένας to produce a haughty spirit, Soph. the heart or mind, as the seat of thought, φρενὶ νοεῖν, ἐπίστασθαι Il., etc.; μετὰ φρεσὶ μερμηρίζειν Od.; κατὰ φρένα εἰδέναι, γνῶναι Il., etc.; κατὰ φρένα καὶ κατὰ θυμόν, as in Lat. mens animusque, Il.;—hence men lose their φρένες, i. e. their wits, Od.; πλήγη φρένας ἃς πάρος εἶχεν Il.;—so, in Attic, φρενῶν ἀφεστάναι, ἐκστῆναι to be out of oneʼs wits, Soph., Eur.; ποῦ ποτʼ εἰ φρενῶν; satisne sanus es? Soph.; φρενῶν ἐπήβολος in possession of oneʼs senses, Soph.; ἔνδον φρενῶν Eur.; ἐξ ἄκρας φρενός, i. e. superficially, Aesch. of beasts, Il. will, purpose, Soph.